Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.44 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.42 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | AMY2A | P04746 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665157 | 0.93 | TYR (0.52) | TYRLGALS8AMY2A | |
| SCHEMBL7655224 | 0.89 | TYR (0.55) | TYRLGALS8SLC5A1 | |
| SCHEMBL7655201 | 0.89 | TYR (0.48) | TYRLGALS8 | |
| SCHEMBL7658272 | 0.89 | TYR (0.55) | TYRLGALS8SLC5A1 | |
| SCHEMBL7655232 | 0.89 | TYR (0.55) | TYRLGALS8SLC5A1 | |
| SCHEMBL7655205 | 0.89 | TYR (0.48) | TYRLGALS8 | |
| SCHEMBL7664371 | 0.87 | TYR (0.53) | TYRAMY2A | |
| SCHEMBL7654565 | 0.87 | TYR (0.51) | TYRLGALS8 | |
| SCHEMBL7662306 | 0.87 | TYR (0.55) | TYRSLC5A1 | |
| SCHEMBL7662298 | 0.87 | TYR (0.55) | TYRSLC5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492335-B1 | Glycoconjugates from modified camptothecin derivatives (20-O-linkage) | BAYER AKTIENGESELLSCHAFT (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-0934329-B1 | GLYCOCONJUGATES FROM MODIFIED CAMPTOTHECIN DERIVATES (20-O-LINKAGE) | BAYER AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-0939765-B1 | GLYCOCONJUGATES OF MODIFIED CAMPTOTHECIN DERIVATIVES (A- OR B-RING LINKAGE) | BAYER AG (DE) | 2001-12-05 | — | — | EP | disclosed |
| US-6271342-B1 | SERUM STABILITY; FOR TUMOR THERAPY | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-07 | — | — | US | disclosed |
| US-6156754-A | Glycoconjugates of modified camptothecin derivatives (A-or B-ring linkage) | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-05 | — | — | US | disclosed |
| EP-0819135-B1 | SUGAR-MODIFIED CYTOSTATICS | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |