Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.42 |
| ▸ | FNTB | P49356 | 7/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 6/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662366 | 0.97 | FNTA (0.42) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL7661101 | 0.87 | FNTA (0.43) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL7501870 | 0.76 | FNTA (0.43) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL6926261 | 0.76 | GRIN2B (0.54) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL6923102 | 0.75 | GRIN2B (0.53) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL6928071 | 0.75 | FNTA (0.55) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| Hydrochloric Acid SCHEMBL6926446 | 0.74 | GRIN2B (0.53) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL7509424 | 0.72 | FNTA (0.72) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL7507010 | 0.72 | FNTA (0.60) | FNTAFNTBPGGT1BGRIN2BCYP2D6 | |
| SCHEMBL6929325 | 0.72 | SMN1; SMN2 (0.53) | FNTAFNTBPGGT1BGRIN2BCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384061-B1 | HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS | LG CHEMICAL LTD. (KR) | 2002-05-07 | — | — | US | disclosed |