Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667691 | 0.99 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL7658067 | 0.97 | SMN1; SMN2 (0.71) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7873542 | 0.95 | SMN1; SMN2 (0.64) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL7665743 | 0.93 | SMN1; SMN2 (0.74) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7870120 | 0.93 | SMN1; SMN2 (0.65) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7868501 | 0.90 | SMN1; SMN2 (0.68) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7873538 | 0.89 | SMN1; SMN2 (0.56) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7870118 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7868499 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 | |
| SCHEMBL7658059 | 0.82 | SMN1; SMN2 (0.72) | SMN1; SMN2L3MBTL1NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417193-B1 | ISOOXAZOLE CHLOROQUINOLONE DRUGS ANTICARCINOGENIC AGENTS AND ANTITUMOR AGENTS | ELI LILLY AND COMPANY | 2002-07-09 | — | — | US | disclosed |