Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664030 | 0.87 | CACNA1B (0.67) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL7668236 | 0.84 | CACNA1B (0.64) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL25531422 | 0.84 | CACNA1B (1.00) | CACNA1BSLC6A3CTSLFAAHCYP3A4 | |
| SCHEMBL11932026 | 0.84 | CACNA1B (1.00) | CACNA1BSLC6A3CTSLFAAHCYP3A4 | |
| SCHEMBL7656059 | 0.81 | CACNA1B (0.60) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL7390781 | 0.80 | CACNA1B (0.73) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL7383617 | 0.80 | CACNA1B (0.73) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL7383612 | 0.80 | CACNA1B (0.73) | CACNA1BSLC6A3FAAHCYP3A4CYP2D6 | |
| SCHEMBL7666024 | 0.80 | CNR1 (0.60) | EPHX2 | |
| SCHEMBL7319572 | 0.80 | CNR1 (0.60) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | claimed |
| US-6458781-B1 | BLOCKERS CALCIUM CHANNEL ANTAGONISTS FOR STROKES, BRAIN DISORDERS | WARNER-LAMBERT COMPANY | 2002-10-01 | — | — | US | disclosed |