Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.69 |
| ▸ | HTR2A | P28223 | 4/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662474 | 1.00 | CCR3 (0.69) | CCR3HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6774697 | 0.93 | CCR3 (0.79) | CCR3HTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7667508 | 0.88 | CCR3 (0.89) | CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7667502 | 0.88 | CCR3 (0.89) | CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6215640 | 0.82 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL6337783 | 0.81 | CCR3 (1.00) | CCR3HTR2A | |
| SCHEMBL7658995 | 0.81 | CCR3 (0.86) | CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7659000 | 0.81 | CCR3 (0.86) | CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7662140 | 0.81 | CCR3 (0.83) | CCR3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7662133 | 0.81 | CCR3 (0.83) | CCR3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441001-B1 | 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-08-27 | — | — | US | claimed |