Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 12/20 | 0.45 |
| ▸ | F7 | P08709 | 11/20 | 0.45 |
| ▸ | F2 | P00734 | 9/20 | 0.45 |
| ▸ | F10 | P00742 | 9/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688393 | 0.90 | F7 (0.58) | F3F7F2F10PRSS1 | |
| SCHEMBL7663122 | 0.83 | F3 (0.50) | F3F7F2F10PRSS1 | |
| SCHEMBL7655674 | 0.81 | F7 (0.69) | F3F7F2F10PRSS1 | |
| SCHEMBL6295760 | 0.80 | F3 (0.43) | F3F7F2F10PRSS1 | |
| SCHEMBL7656692 | 0.78 | F7 (0.65) | F3F7F2F10PRSS1 | |
| SCHEMBL7665736 | 0.76 | F3 (0.51) | F3F7F2F10PRSS1 | |
| SCHEMBL6300738 | 0.75 | F3 (0.41) | F3F7F2F10PRSS1 | |
| SCHEMBL7685838 | 0.73 | F3 (0.51) | F3F7F2F10PRSS1 | |
| SCHEMBL7685841 | 0.73 | F3 (0.51) | F3F7F2F10PRSS1 | |
| SCHEMBL18082334 | 0.73 | KMT2A (0.75) | KMT2AMEN1ACACBGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |