Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.64 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7664444 | 1.00 | GRM1 (0.64) | GRM1KDM1AMAOAMAOBSLC6A4 | |
| SCHEMBL7659762 | 0.80 | GRM1 (0.43) | GRM1MAOAMAOB | |
| SCHEMBL7659771 | 0.80 | GRM1 (0.43) | GRM1MAOAMAOB | |
| SCHEMBL7659766 | 0.80 | GRM1 (0.43) | GRM1MAOAMAOB | |
| SCHEMBL7385755 | 0.80 | GRM1 (0.78) | GRM1KDM1AMAOAMAOBCYP1A2 | |
| SCHEMBL7687343 | 0.78 | GRM1 (0.65) | GRM1KDM1AMAOAMAOBSLC6A4 | |
| SCHEMBL7679875 | 0.78 | GRM1 (0.65) | GRM1KDM1AMAOAMAOBSLC6A4 | |
| SCHEMBL7679872 | 0.78 | GRM1 (0.65) | GRM1KDM1AMAOAMAOBSLC6A4 | |
| SCHEMBL7669527 | 0.78 | GRM1 (0.61) | GRM1KDM1AMAOAMAOBHRH3 | |
| SCHEMBL7422069 | 0.78 | GRM1 (0.61) | GRM1KDM1AMAOAMAOBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376539-B1 | ANTIISCHEMIC AGENTS, CENTRAL NERVOUS SYSTEM DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-23 | — | — | US | disclosed |