Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665238 | 0.96 | HTR2A (0.44) | GRIN2BCHRM5HTR2AALDH1A1TSHR | |
| SCHEMBL7666383 | 0.95 | HTR2A (0.46) | GRIN2BCHRM5HTR2AALDH1A1GPR3 | |
| SCHEMBL7663418 | 0.92 | GRIN2B (0.43) | GRIN2BCHRM5ALDH1A1TSHRGPR3 | |
| SCHEMBL7660282 | 0.87 | GRIN2B (0.45) | GRIN2BCHRM5ALDH1A1TSHRGPR3 | |
| SCHEMBL7659968 | 0.85 | MAOB (0.53) | GRIN2BALDH1A1GPR3MAOBHDAC3 | |
| SCHEMBL7664962 | 0.82 | MAOB (0.51) | ALDH1A1GPR3MAOB | |
| SCHEMBL5686922 | 0.82 | HRH3 (0.47) | CHRM5ALDH1A1TSHRS1PR1SLC6A4 | |
| SCHEMBL7656564 | 0.81 | MAOB (0.50) | ALDH1A1TSHRMAOB | |
| SCHEMBL7661597 | 0.80 | PLK1 (0.39) | GPR3MAOBMAOAS1PR1 | |
| SCHEMBL7668487 | 0.79 | MAOB (0.50) | GRIN2BCHRM5GPR3MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495220-B2 | WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS | CLARIANT INTERNATIONAL LTD. (CH) | 2002-12-17 | — | — | US | disclosed |
| US-20010023935-A1 | With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers | CLARIANT INTERNATIONAL LTD. (CH) | 2001-09-27 | — | — | US | disclosed |