Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655654 | 0.86 | TSHR (0.39) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL18177935 | 0.72 | CYP3A4 (0.38) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL18182325 | 0.72 | TSHR (0.41) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL18177929 | 0.70 | TSHR (0.41) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL18166807 | 0.70 | — | — | |
| SCHEMBL18166808 | 0.70 | — | — | |
| SCHEMBL18177942 | 0.69 | TSHR (0.39) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL1262441 | 0.68 | CYP3A4 (0.41) | TSHRCYP3A4PKMSMN1; SMN2TDP1 | |
| SCHEMBL18177986 | 0.65 | — | — | |
| SCHEMBL11239793 | 0.65 | TSHR (0.44) | TSHRCYP3A4PKMSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444837-B1 | VIRICIDES | UNIVERSITY OF SOUTHERN CALIFORNIA | 2002-09-03 | — | — | US | disclosed |