Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 10/20 | 0.73 |
| ▸ | GRIA2 | P42262 | 10/20 | 0.73 |
| ▸ | GRIA3 | P42263 | 10/20 | 0.73 |
| ▸ | GRIA4 | P48058 | 10/20 | 0.73 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.64 |
| ▸ | GRIK2 | Q13002 | 9/20 | 0.64 |
| ▸ | GRIK5 | Q16478 | 8/20 | 0.64 |
| ▸ | GRIK3 | Q13003 | 7/20 | 0.64 |
| ▸ | GRIK4 | Q16099 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668821 | 0.92 | GRIA1 (0.79) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7664438 | 0.91 | GRIK1 (0.77) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7668566 | 0.86 | GRIA1 (0.75) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7663264 | 0.85 | GRIA1 (0.74) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7666995 | 0.85 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7483788 | 0.82 | GRIA1 (0.81) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7479164 | 0.81 | GRIK1 (0.81) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7480816 | 0.81 | GRIK1 (0.83) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610087 | 0.79 | GRIK1 (0.82) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8610384 | 0.79 | GRIA1 (0.79) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407109-B1 | ANTIEPILETIC, ANTIDEPRESSANT, AND ANXIOLYTIC AGENTS; PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ABBOTT LABORATORIES | 2002-06-18 | — | — | US | disclosed |