SCHEMBL7666183

SCHEMBL7666183

[CH]=C(CC)c1ccccc1N(CC)CC

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 5/20 0.34
TSHR P16473 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MAPT P10636 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
LMNA P02545 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP3A4 P08684 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32
AR P10275 1/20 0.31
BRPF1 P55201 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7673381 0.84 TP53 (0.36) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL3274550 0.80 TP53 (0.36) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL2493417 0.79 TSHR (0.42) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL7662268 0.78 TP53 (0.36) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL9126049 0.77 TP53 (0.38) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL2696139 0.77 TP53 (0.42) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL166160 0.76 TP53 (0.61) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL136256 0.74 TP53 (0.35) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL1668024 0.74 TP53 (0.53) TP53TSHRSMN1; SMN2MAPTALDH1A1
SCHEMBL26444540 0.74 SMN1; SMN2 (0.44) TP53TSHRSMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500816-B1 ANTITUMOR NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2002-12-31 US disclosed
EP-1120119-A1 REMEDIES FOR PHOTOCHEMOTHERAPY Nippon Kayaku Kabushiki Kaisha (JP) 2001-08-01 EP disclosed
EP-0554627-B1 Aminium salt compound and optical recording medium CANON KK (JP) 1999-03-10 EP disclosed
US-5846730-A Labelled complex CANON KABUSHIKI KAISHA (JP) 1998-12-08 US disclosed
EP-0463784-B1 Optical recording medium, optical recording method, and optical reproducing method CANON KK (JP) 1998-10-14 EP disclosed
EP-0519474-B1 Labeled complex CANON KK (JP) 1998-09-16 EP disclosed
US-5700647-A LABELED COMPLEX FOR DETECTING SUBJECT COMPOUND TO BE ANALYZED BY OPTICAL MEANS USING NEAR-INFRARED RADIATION COMPRISING SUBSTANCE FROM LIVING ORGANISM AND LABELING AGENT FIXED THERETO CANON KABUSHIKI KAISHA (JP) 1997-12-23 US disclosed
US-5605732-A METAL COMPLEX DYE CANON KABUSHIKI KAISHA (JP) 1997-02-25 US disclosed
US-5572492-A Optical recording and reproducing method utilizing recording medium including recording regions formed by localized co-melted mixture of non-reactant materials CANON KABUSHIKI KAISHA (JP) 1996-11-05 US disclosed
US-5512446-A STORAGE STABILITY CANON KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
US-5100766-A Subbing Layer Laminate of Polysiloxane and Polysiloxane Substituted with Acrylic Resin, Thermoconductivity CANON KABUSHIKI KAISHA (JP) 1992-03-31 US disclosed
US-5085925-A With thermoplastic bonding layer containing tackifier resin and copolymer of ethylene and acrylic acid or acrylate or terpolymer with maleic anhydride CANON KABUSHIKI KAISHA (JP) 1992-02-04 US disclosed
US-5079127-A Methine Dyes CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
US-5079128-A Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance CANON KABUSHIKI KAISHA (JP) 1992-01-07 US disclosed
EP-0463784-A2 Optical recording medium, optical recording method, and optical reproducing method CANON KABUSHIKI KAISHA (JP) 1992-01-02 EP disclosed
US-4944981-A Containing polymethine compound CANON KABUSHIKI KAISHA (JP) 1990-07-31 US disclosed
US-4931337-A CONTAINING ORGANIC MATERIAL, ADHESIVE CANON KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
US-4923390-A AMINE OR QUATERNARY SALTS USED AS PHOTOSTABILIZERS WITH METHINE DYES; HEAT AND RADIATION RESISTANCE; DURABILITY; OPTICAL CARDS AND DISKS; LASERS CANON KABUSHIKI KAISHA (JP) 1990-05-08 US disclosed
EP-0278763-A2 Information recording medium CANON KABUSHIKI KAISHA (JP) 1988-08-17 EP disclosed
EP-0264198-A2 Optical information recording medium CANON KABUSHIKI KAISHA (JP) 1988-04-20 EP disclosed