SCHEMBL7666203

SCHEMBL7666203

Cc1ccc2c(ccc3cc(F)ccc32)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 6/20 0.52
CYP2A6 P11509 5/20 0.52
KDM4E B2RXH2 3/20 0.50
LMNA P02545 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
GAA P10253 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KIF11 P52732 1/20 0.48
ACHE P22303 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
ITK Q08881 1/20 0.43
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
KCNH2 Q12809 1/20 0.39
MAOB P27338 1/20 0.39
MAPT P10636 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
NPC1 O15118 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL806323 0.88 CYP1A2 (0.68) CYP1A2CYP2A6KDM4ELMNAALDH1A1
Ammonia Solution, Strong SCHEMBL27919196 0.86 CYP1A2 (0.65) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL8153220 0.86 CYP2A6 (0.70) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL607927 0.85 CYP1A2 (0.71) CYP1A2CYP2A6KDM4ELMNAALDH1A1
Ammonia Solution, Strong SCHEMBL27937804 0.84 CYP2A6 (0.67) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL12017095 0.84 CYP2A6 (0.62) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL12405217 0.83 CYP1A2 (0.55) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL12260024 0.83 CYP1A2 (0.55) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL597341 0.83 CYP1A2 (0.67) CYP1A2CYP2A6KDM4ELMNAALDH1A1
SCHEMBL12277510 0.83 CYP1A2 (0.55) CYP1A2CYP2A6KDM4ELMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495220-B2 WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS CLARIANT INTERNATIONAL LTD. (CH) 2002-12-17 US disclosed
US-20010023935-A1 With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers CLARIANT INTERNATIONAL LTD. (CH) 2001-09-27 US disclosed