Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7666214 | 1.00 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15255864 | 0.92 | HDAC3 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7568425 | 0.91 | CYP2C9 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7568419 | 0.91 | CYP2C9 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL10429862 | 0.90 | CYP2C9 (0.44) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9501064 | 0.90 | CYP2C9 (0.40) | CYP2C9ESR2MAPTMEN1MAPK1 | |
| SCHEMBL9561423 | 0.90 | CYP2C9 (0.40) | CYP2C9ESR2MAPTMEN1MAPK1 | |
| SCHEMBL9245531 | 0.89 | CYP2C9 (0.39) | CYP2C9ESR2MAPTMEN1MAPK1 | |
| SCHEMBL9245524 | 0.89 | CYP2C9 (0.39) | CYP2C9ESR2MAPTMEN1MAPK1 | |
| SCHEMBL9247183 | 0.88 | SPHK1 (0.39) | CYP2C9ESR2MAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |