Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667184 | 1.00 | NPC1 (0.59) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL10102036 | 0.81 | NPC1 (0.50) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL17257560 | 0.80 | NPC1 (0.89) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL17257559 | 0.80 | NPC1 (0.89) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL7669499 | 0.79 | NPC1 (0.46) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL7669498 | 0.79 | NPC1 (0.46) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL7672574 | 0.79 | NPC1 (0.73) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL7674107 | 0.79 | NPC1 (0.48) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL7672573 | 0.79 | NPC1 (0.73) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG | |
| SCHEMBL10241911 | 0.79 | NPC1 (0.50) | NPC1RAB9AL3MBTL1SMN1; SMN2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489487-B1 | AGRICULTURAL OR HORTICULTURAL FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-03 | — | — | US | disclosed |
| EP-1103548-A1 | TRIAZOLONE DERIVATIVES, USE THEREOF, AND INTERMEDIATE THEREFOR | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-05-30 | — | — | EP | disclosed |