Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660726 | 1.00 | SMN1; SMN2 (0.71) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7658059 | 0.99 | SMN1; SMN2 (0.72) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7665740 | 0.96 | SMN1; SMN2 (0.74) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL7873538 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL7870118 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL7868499 | 0.85 | SMN1; SMN2 (0.59) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7662844 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7668040 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7668956 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2GLAPKML3MBTL1NPC1 | |
| SCHEMBL7667691 | 0.83 | SMN1; SMN2 (0.68) | SMN1; SMN2GLAPKML3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6417193-B1 | ISOOXAZOLE CHLOROQUINOLONE DRUGS ANTICARCINOGENIC AGENTS AND ANTITUMOR AGENTS | ELI LILLY AND COMPANY | 2002-07-09 | — | — | US | disclosed |