Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668264 | 1.00 | TLR4 (0.34) | TLR4CCNT1CDK9HTR1AHTR7 | |
| SCHEMBL15256169 | 0.90 | TLR4 (0.35) | TLR4HTR1AHTR7 | |
| SCHEMBL2909344 | 0.89 | TLR4 (0.34) | TLR4 | |
| SCHEMBL14494608 | 0.89 | TLR4 (0.34) | TLR4 | |
| SCHEMBL2909350 | 0.89 | TLR4 (0.34) | TLR4 | |
| SCHEMBL15256181 | 0.87 | HDAC3 (0.37) | — | |
| SCHEMBL17075735 | 0.86 | TLR4 (0.36) | TLR4 | |
| SCHEMBL17075733 | 0.86 | TLR4 (0.36) | TLR4 | |
| SCHEMBL732054 | 0.86 | CCNT1 (0.35) | CCNT1CDK9HTR1AHTR7 | |
| SCHEMBL4400181 | 0.83 | TLR4 (0.34) | TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |