Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 12/20 | 0.75 |
| ▸ | GRIA2 | P42262 | 12/20 | 0.75 |
| ▸ | GRIA3 | P42263 | 12/20 | 0.75 |
| ▸ | GRIA4 | P48058 | 12/20 | 0.75 |
| ▸ | GRIK1 | P39086 | 11/20 | 0.74 |
| ▸ | GRIK2 | Q13002 | 11/20 | 0.74 |
| ▸ | GRIK5 | Q16478 | 10/20 | 0.74 |
| ▸ | GRIK3 | Q13003 | 10/20 | 0.74 |
| ▸ | GRIK4 | Q16099 | 5/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662232 | 0.91 | GRIA1 (0.87) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7668566 | 0.89 | GRIA1 (0.75) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7483220 | 0.86 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL2053498 | 0.85 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7664438 | 0.85 | GRIK1 (0.77) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7668821 | 0.84 | GRIA1 (0.79) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7662246 | 0.84 | GRIA1 (0.86) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL7663264 | 0.81 | GRIA1 (0.74) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8672098 | 0.80 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 | |
| SCHEMBL8673956 | 0.80 | GRIA1 (1.00) | GRIA1GRIA2GRIA3GRIA4GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407109-B1 | ANTIEPILETIC, ANTIDEPRESSANT, AND ANXIOLYTIC AGENTS; PSYCHOLOGICAL AND NERVOUS SYSTEM DISORDERS | ABBOTT LABORATORIES | 2002-06-18 | — | — | US | disclosed |