Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.58 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.44 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.44 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496949 | 0.87 | CACNA1B (0.67) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7532827 | 0.84 | CACNA1B (0.69) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL4502898 | 0.84 | CACNA1B (0.81) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7667045 | 0.84 | CACNA1B (0.54) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL5855031 | 0.84 | CACNA1B (0.63) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7533787 | 0.83 | CACNA1B (0.65) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7660929 | 0.83 | CACNA1B (0.73) | CACNA1BCACNA1CADORA3 | |
| SCHEMBL7660932 | 0.83 | CACNA1B (0.73) | CACNA1BCACNA1CADORA3 | |
| SCHEMBL7663100 | 0.83 | CACNA1B (0.54) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7525770 | 0.82 | CACNA1B (0.64) | CACNA1BCACNA1FCACNA1DCACNA1SCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1043314-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-10-11 | — | — | EP | disclosed |