Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL7669140 | 1.00 | FLT3 (0.40) | FLT3KDM2BSMN1; SMN2MAPTLMNA | |
| SCHEMBL6289119 | 0.95 | KDM2B (0.42) | FLT3KDM2BSMN1; SMN2MAPTLMNA | |
| SCHEMBL6289118 | 0.95 | KDM2B (0.42) | FLT3KDM2BSMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL4793465 | 0.94 | KDM2B (0.41) | FLT3KDM2BSMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL4793469 | 0.94 | KDM2B (0.41) | FLT3KDM2BSMN1; SMN2MAPTLMNA | |
| Oxalic Acid SCHEMBL6288887 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTLMNAKMT2ACYP1A2 | |
| Oxalic Acid SCHEMBL4772709 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2MAPTLMNAKMT2ACYP1A2 | |
| Oxalic Acid SCHEMBL4772102 | 0.86 | KDM4E (0.51) | FLT3SMN1; SMN2MAPTLMNAKMT2A | |
| Oxalic Acid SCHEMBL4772095 | 0.86 | KDM4E (0.51) | FLT3SMN1; SMN2MAPTLMNAKMT2A | |
| Oxalic Acid SCHEMBL4772097 | 0.86 | KDM4E (0.51) | FLT3SMN1; SMN2MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340759-B1 | ANTISPASMODIC AGENTS | EISAI CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |