SCHEMBL7669693

SCHEMBL7669693

OC1(F)CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91319 0.96
SCHEMBL17970603 0.87
SCHEMBL8590083 0.87
SCHEMBL16409171 0.72
SCHEMBL6901576 0.67
SCHEMBL12548979 0.67
SCHEMBL25438483 0.65
SCHEMBL25973681 0.65
SCHEMBL29282995 0.65
Methyl Alcohol SCHEMBL29281330 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239778-A1 GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-07-18 US disclosed
WO-2024148149-A2 COMPOSITIONS AND METHODS FOR CONTROLLING GLUCOSE LEVELS SIRTSEI PHARMACEUTICALS, INC. (US) 2024-07-11 WO disclosed
US-11993593-B2 Griseofulvin compound and pharmaceutical use thereof DAIICHI SANKYO COMPANY, LIMITED (JP) 2024-05-28 US disclosed
US-20240158418-A1 EGFR Degraders to Treat Cancer Metastasis to the Brain or CNS C4 THERAPEUTICS, INC. (US) 2024-05-16 US disclosed
EP-4347044-A2 EGFR DEGRADERS TO TREAT CANCER METASTASIS TO THE BRAIN OR CNS C4 Therapeutics, Inc. (US) 2024-04-10 EP disclosed
WO-2024059705-A1 COMPOSITIONS AND METHODS FOR TREATING DEPRESSION IN FEMALES SIRTSEI PHARMACEUTICALS, INC. (US) 2024-03-21 WO disclosed
US-20240076300-A1 ISOINDOLINONE AND INDAZOLE COMPOUNDS FOR THE DEGRADATION OF EGFR C4 THERAPEUTICS, INC. (US) 2024-03-07 US disclosed
WO-2024026443-A1 COMPOSITIONS AND METHODS FOR IMPROVING MEMORY AND COGNITION SIRTSEI PHARMACEUTICALS, INC. (US) 2024-02-01 WO disclosed
US-11673902-B2 Isoindolinone and indazole compounds for the degradation of EGFR C4 THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-20230136792-A1 COMPOSITIONS AND METHODS FOR TREATING AGE-RELATED DISEASES AND PREMATURE AGING DISORDERS SIRTSEI PHARMACEUTICALS, INC. 2023-05-04 US disclosed
WO-2019000236-A1 3-(1H-PYRAZOL-4-YL)PYRIDINE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR MERCK SHARP & DOHME CORP. (US) 2019-01-03 WO disclosed
EP-2670752-B1 PYRROLOPYRAZINE-SPIROCYCLIC PIPERIDINE AMIDES AS MODULATORS OF ION CHANNELS VERTEX PHARMA (US) 2016-03-16 EP disclosed
CN-103827110-A N-(3-(2-amino-6,6-difluoro-4,4a,5,6,7,7a-hexahydro-cyclopenta[e][1,3]oxazin-4-yl)-phenyl)-amides as bace1 inhibitors HOFFMANN LA ROCHE 2014-05-28 CN disclosed
US-20100203445-A1 NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-08-12 US disclosed
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-6444616-B1 HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 2002-09-03 US disclosed
US-6130225-A Substituted p-trifluoromethylphenyluracils BAYER AKTIENGESELLSCHAFT (DE) 2000-10-10 US disclosed
EP-0923562-A1 SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS BAYER AG (DE) 1999-06-23 EP disclosed
WO-1998006706-A1 SUBSTITUTED P-TRIFLUOROMETHYLPHENYLURACILS BAYER AKTIENGESELLSCHAFT (DE) 1998-02-19 WO disclosed