Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 19/20 | 0.83 |
| ▸ | TACR1 | P25103 | 4/20 | 0.83 |
| ▸ | TACR3 | P29371 | 4/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669815 | 1.00 | TACR2 (0.83) | TACR2TACR1TACR3 | |
| SCHEMBL7673760 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL7673763 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL7666692 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL7666681 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL7673768 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL29374317 | 0.90 | TACR2 (0.79) | TACR2TACR1TACR3 | |
| SCHEMBL7674606 | 0.89 | TACR2 (0.78) | TACR2TACR1TACR3 | |
| SCHEMBL7674607 | 0.89 | TACR2 (0.78) | TACR2TACR1TACR3 | |
| SCHEMBL13964807 | 0.89 | TACR2 (0.67) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365602-B1 | FOR THERAPY OF DEPRESSION, ANXIETY, ASTHMA, PAIN, INFLAMMATION, URINARY INCONTINENCE AND OTHER DISEASE CONDITIONS | ASTRA ZENECA AB (SE) | 2002-04-02 | — | — | US | disclosed |
| EP-1097137-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | AstraZeneca AB (SE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000002859-A1 | N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2000-01-20 | — | — | WO | disclosed |