Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 5/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7670195 | 1.00 | ADORA1 (0.47) | ADORA1IGF1RMAPK1XDHEGFR | |
| SCHEMBL9035165 | 0.86 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL9035159 | 0.86 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL9035178 | 0.86 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7660818 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7660825 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7660830 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7670232 | 0.83 | ADORA1 (0.53) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7665031 | 0.83 | ADORA1 (0.53) | ADORA1IGF1RMAPK1EGFRAKT1 | |
| SCHEMBL7665028 | 0.83 | ADORA1 (0.53) | ADORA1IGF1RMAPK1EGFRAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |