SCHEMBL7670288

SCHEMBL7670288

CS/C(=C\[N+](=O)[O-])NCc1cnc(Cl)s1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.46
ALDH1A1 P00352 8/20 0.46
HTT P42858 2/20 0.46
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7662389 1.00 MAPT (0.46) MAPTALDH1A1HTTLMNARECQL
SCHEMBL7671870 0.82 MAPT (0.42) MAPTALDH1A1LMNARECQLSMN1; SMN2
SCHEMBL7665692 0.81 RECQL (0.39) MAPTALDH1A1LMNARECQLL3MBTL1
SCHEMBL7671648 0.81 RECQL (0.39) MAPTALDH1A1LMNARECQLL3MBTL1
SCHEMBL7670470 0.80 RECQL (0.38) MAPTALDH1A1LMNARECQLL3MBTL1
SCHEMBL7666642 0.80 RECQL (0.38) MAPTALDH1A1LMNARECQLL3MBTL1
SCHEMBL7840104 0.77 RECQL (0.38) MAPTALDH1A1LMNARECQLSMN1; SMN2
SCHEMBL7840103 0.77 RECQL (0.38) MAPTALDH1A1LMNARECQLSMN1; SMN2
SCHEMBL9718780 0.77 RECQL (0.36) MAPTALDH1A1LMNARECQLL3MBTL1
SCHEMBL8401700 0.77 RECQL (0.36) MAPTALDH1A1LMNARECQLL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6407248-B1 INSECTICIDES, MITICIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2002-06-18 US disclosed
US-6124297-A COMBATTING INSECTS OR MITES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
US-5935981-A INSECTICIDAL/MITICIDAL ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1999-08-10 US disclosed
US-5849768-A α-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-12-15 US disclosed
EP-0529680-B1 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1998-05-13 EP disclosed
EP-0302389-B1 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1993-12-22 EP disclosed
US-5214152-A Insecticides, miticides TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-05-25 US disclosed
EP-0529680-A2 Intermediates, their production and their use for preparing alpha-unsaturated amines TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-03-03 EP disclosed
US-5175301-A Insecticide, miticide, pesticide TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-12-29 US disclosed
EP-0509559-A2 Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-21 EP disclosed
EP-0302389-A2 Alpha-unsaturated amines, their production and use Takeda Chemical Industries, Ltd. (JP) 1989-02-08 EP disclosed