Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 18/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | HPN | P05981 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675327 | 0.92 | F2 (0.59) | F2PAX8HDAC1 | |
| SCHEMBL7670064 | 0.86 | F2 (0.58) | F2PAX8F10HPNPRSS1 | |
| SCHEMBL7673186 | 0.84 | F2 (0.60) | F2PAX8F10 | |
| SCHEMBL7670676 | 0.83 | F2 (0.69) | F2 | |
| SCHEMBL6974717 | 0.82 | F2 (0.62) | F2PAX8 | |
| SCHEMBL7668884 | 0.82 | F2 (0.59) | F2PAX8 | |
| SCHEMBL6986249 | 0.82 | F2 (0.61) | F2PAX8 | |
| SCHEMBL6635670 | 0.81 | F2 (0.74) | F2F10HPNPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL6977321 | 0.80 | F2 (0.67) | F2 | |
| SCHEMBL7675969 | 0.80 | F2 (0.62) | F2PAX8F10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6365584-B1 | FOR PROPHYLAXIS AND THERAPY OF INFLAMMATORY AND/OR ALLERGIC DISEASES, LUNG FIBROSIS, FIBROSING ALVEOLITIS AND SCARRING, COLLAGENOSES SUCH AS LUPUS ERYTHEMATODES AND SCLERODERMIA AS WELL AS ARTERIOSCLEROSIS, PSORIASIS AND NEOPLASM | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-04-02 | — | — | US | disclosed |