Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671832 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL7671826 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL11912325 | 0.95 | KDM4E (0.41) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL13119881 | 0.95 | KDM4E (0.41) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL13211811 | 0.95 | KDM4E (0.41) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL10702946 | 0.95 | KDM4E (0.41) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL13105834 | 0.95 | KDM4E (0.41) | KDM4EALDH1A1HKDC1TDP1SAE1 | |
| SCHEMBL7668019 | 0.91 | — | — | |
| SCHEMBL7665603 | 0.91 | TBXA2R (0.37) | ALDH1A1TBXA2RPTGDRPTGER4PTGER3 | |
| SCHEMBL7668024 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359181-B1 | THERAPY FOR VISION DEFECTS | ALLERGAN SALES, INC. | 2002-03-19 | — | — | US | disclosed |
| US-6307092-B1 | POTENT OCULAR HYPOTENSIVES AND ARE PARTICULARLY SUITED FOR THE MANAGEMENT OF GLAUCOMA. | ALLERGAN SALES, INC. | 2001-10-23 | — | — | US | disclosed |
| US-6248783-B1 | GLAUCOMA THERAPY | ALLERGAN SALES, INC. | 2001-06-19 | — | — | US | disclosed |