Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.56 |
| ▸ | CDK4 | P11802 | 5/20 | 0.54 |
| ▸ | AKT1 | P31749 | 8/20 | 0.51 |
| ▸ | AKT2 | P31751 | 8/20 | 0.51 |
| ▸ | USP7 | Q93009 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683359 | 0.93 | CDK2 (0.59) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7676756 | 0.90 | CDK2 (0.56) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7680211 | 0.90 | CDK2 (0.60) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7673606 | 0.90 | CDK2 (0.54) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7467961 | 0.88 | AKT1 (0.56) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7676709 | 0.87 | USP7 (0.60) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7678849 | 0.87 | AKT1 (0.55) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7676382 | 0.87 | USP7 (0.59) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7674003 | 0.86 | CDK2 (0.53) | CDK2CDK4AKT1AKT2USP7 | |
| SCHEMBL7682754 | 0.86 | CDK2 (0.58) | CDK2CDK4AKT1AKT2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |