SCHEMBL767363

SCHEMBL767363

C1=NC2=CCNC2=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL208333 0.68
SCHEMBL30142537 0.52
SCHEMBL19724702 0.41
Hydrochloric Acid SCHEMBL31565009 0.31
Hydrochloric Acid SCHEMBL6244319 0.31
Hydrochloric Acid SCHEMBL1449238 0.31
SCHEMBL3279831 0.31
Hydrochloric Acid SCHEMBL72335 0.31
SCHEMBL12992748 0.29
SCHEMBL31437084 0.27 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261724-A1 HETEROCYCLE PHENYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS MERCK SHARP & DOHME LLC 2010-10-14 US claimed
US-20100249176-A1 HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS BARROW JAMES C 2010-09-30 US claimed
EP-2212291-A1 HETEROCYCLE PHENYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS Merck Sharp & Dohme Corp. (US) 2010-08-04 EP claimed
EP-2212293-A1 HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS Merck Sharp & Dohme Corp. (US) 2010-08-04 EP claimed
WO-2009054983-A1 HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS MERCK & CO., INC. (US) 2009-04-30 WO claimed
WO-2009054984-A1 HETEROCYCLE PHENYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS MERCK & CO., INC. (US) 2009-04-30 WO claimed
JP-62205080-A None JP disclosed
JP-62212389-A None JP disclosed
JP-62207276-A None JP disclosed
JP-62207275-A None JP disclosed
JP-63112618-A None JP disclosed
EP-3856342-B1 BICYCLIC DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS RICHTER GEDEON NYRT (HU) 2025-12-10 EP disclosed
US-20250288949-A1 Gas Separation Membrane SEIKO EPSON CORPORATION (JP) 2025-09-18 US disclosed
WO-2009054983-A1 HETEROCYCLE AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS MERCK & CO., INC. (US) 2009-04-30 WO disclosed
WO-2009054984-A1 HETEROCYCLE PHENYL AMIDE T-TYPE CALCIUM CHANNEL ANTAGONISTS MERCK & CO., INC. (US) 2009-04-30 WO disclosed
JP-S63112618-A PRODUCTION OF N-ALKYL-SUBSTITUTED DIHYDROPYRROLOPYRROLE POLYMER SUMITOMO CHEM CO LTD 1988-05-17 JP disclosed
JP-S62212389-A N-ALKYLDIHYDROPYRROLOPYRROLE COMPOUND AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1987-09-18 JP disclosed
JP-S62207276-A N,N'-DIALKYLDIHYDROPYRROLOPYRROLE COMPOUND AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1987-09-11 JP disclosed
JP-S62207275-A 2-ACYLDIHYDROYRROLOPYRROLE COMPOUND AND PRODUCTION THEREOF SUMITOMO CHEM CO LTD 1987-09-11 JP disclosed
JP-S62205080-A PRODUCTION OF N,N'-DIMETHYLDIHYDROPYRROLOPYRROLE SUMITOMO CHEM CO LTD 1987-09-09 JP disclosed