Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.61 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 4/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650306 | 0.93 | PTPN1 (0.51) | PTPN1PTPN22ACECTSSCTSK | |
| SCHEMBL7672421 | 0.92 | PTPN1 (0.58) | PTPN1PTPN22CTSSCTSKCTSB | |
| SCHEMBL7680157 | 0.91 | PTPN1 (0.56) | PTPN1PTPN22ACECTSSCTSK | |
| SCHEMBL4650261 | 0.87 | PTPN1 (0.51) | PTPN1PTPN22ACECTSSCTSK | |
| SCHEMBL7117053 | 0.86 | PTPN1 (0.52) | PTPN1PTPN22CTSSCTSKCTSB | |
| SCHEMBL6571372 | 0.83 | PTPN1 (0.88) | PTPN1PTPN22 | |
| SCHEMBL4650405 | 0.82 | PTPN1 (0.53) | PTPN1PTPN22CTSSCTSKCTSB | |
| Methoxymethane SCHEMBL11521996 | 0.81 | ACE (0.69) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL2367371 | 0.81 | ACE (0.72) | ACECTSSCTSKCTSBCTSL | |
| SCHEMBL21219305 | 0.81 | ACE (0.72) | ACECTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |