Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18589316 | 0.83 | F2 (0.57) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7678638 | 0.83 | F2 (0.51) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7672610 | 0.82 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7678613 | 0.80 | MEN1 (0.57) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7679148 | 0.79 | F2 (0.69) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7676670 | 0.78 | HTT (0.58) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL8210799 | 0.78 | CA12 (0.54) | KDM4EALDH1A1HPGDHSD17B10MAOB | |
| SCHEMBL16864729 | 0.78 | F2 (0.57) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL7681934 | 0.78 | F2 (0.49) | MEN1KMT2AKDM4EALDH1A1POLB | |
| SCHEMBL18607766 | 0.78 | F2 (0.49) | MEN1KMT2AKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |