Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672610 | 0.83 | MEN1 (0.48) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7676670 | 0.82 | HTT (0.58) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7678613 | 0.82 | MEN1 (0.57) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7675600 | 0.81 | F2 (0.53) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL18589316 | 0.80 | F2 (0.57) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7682058 | 0.78 | KDM4E (0.71) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7679148 | 0.78 | F2 (0.69) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7672606 | 0.78 | F2 (0.50) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16864729 | 0.77 | F2 (0.57) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL7674628 | 0.77 | F2 (0.51) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |