Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.84 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042465 | 0.92 | NPY1R (1.00) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7602720 | 0.89 | NPY1R (0.67) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7044512 | 0.85 | NPY1R (1.00) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7043662 | 0.85 | NPY1R (0.76) | NPY1RCRHR1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7041794 | 0.84 | NPY1R (0.98) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7045687 | 0.83 | NPY1R (1.00) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7037686 | 0.82 | NPY1R (0.98) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL7039372 | 0.82 | NPY1R (0.80) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7044337 | 0.82 | NPY1R (0.81) | NPY1RUSP2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7110387 | 0.81 | NPY1R (0.62) | NPY1RUSP2ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372743-B1 | EATING DISORDERS, HYPOTENSIVE AGENTS AND CARDIOVASCULAR DISORDERS | NEUROGEN CORPORATION | 2002-04-16 | — | — | US | claimed |