Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675238 | 1.00 | GAA (0.47) | GAAMAPTGFERTP53TSHR | |
| SCHEMBL5833441 | 0.78 | MAPT (0.54) | GAAMAPTGFERTP53TSHR | |
| SCHEMBL28317750 | 0.74 | MAPT (0.53) | GAAMAPTGFERTP53EPHX1 | |
| SCHEMBL1242953 | 0.71 | SMN1; SMN2 (0.58) | GAAMAPTGFERTP53TSHR | |
| SCHEMBL28147643 | 0.71 | NAPRT (0.54) | GAAMAPTTP53TSHREPHX1 | |
| Phenylurea SCHEMBL54471 | 0.71 | GAA (0.83) | GAAMAPTGFERTP53TSHR | |
| Phenylurea SCHEMBL27886541 | 0.71 | GAA (0.83) | GAAMAPTGFERTP53TSHR | |
| Phenylurea SCHEMBL28237284 | 0.71 | GAA (0.83) | GAAMAPTGFERTP53TSHR | |
| Phenylurea SCHEMBL28620153 | 0.69 | GAA (0.79) | GAAMAPTGFERTP53TSHR | |
| Phenylurea SCHEMBL7531144 | 0.69 | GAA (0.79) | GAAMAPTGFERTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414013-B1 | KINASE INHIBITORS; ANTICANCER AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-07-02 | — | — | US | disclosed |