⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873752 | 0.79 | KDM4E (0.52) | — | |
| SCHEMBL30831319 | 0.78 | — | — | |
| SCHEMBL17959496 | 0.78 | — | — | |
| SCHEMBL29142160 | 0.76 | — | — | |
| SCHEMBL10820280 | 0.76 | — | — | |
| SCHEMBL573755 | 0.76 | — | — | |
| SCHEMBL28556684 | 0.76 | — | — | |
| SCHEMBL12498192 | 0.76 | — | — | |
| SCHEMBL1491435 | 0.76 | — | — | |
| SCHEMBL27792519 | 0.76 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |