Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 8/20 | 0.77 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.77 |
| ▸ | ITGAL | P20701 | 8/20 | 0.77 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675648 | 1.00 | ITGB2 (0.77) | ITGB2ICAM1ITGALEGFRKMT2A | |
| SCHEMBL6765914 | 0.88 | ITGB2 (0.76) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL6765916 | 0.88 | ITGB2 (0.76) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL5830932 | 0.88 | ITGB2 (1.00) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL6759553 | 0.87 | ITGB2 (0.74) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL6759534 | 0.87 | ITGB2 (0.61) | ITGB2ICAM1ITGALEGFRKMT2A | |
| SCHEMBL6759529 | 0.87 | ITGB2 (0.61) | ITGB2ICAM1ITGALEGFRKMT2A | |
| SCHEMBL6759557 | 0.87 | ITGB2 (0.74) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL6763181 | 0.86 | ITGB2 (0.98) | ITGB2ICAM1ITGALKMT2AHDAC1 | |
| SCHEMBL6763184 | 0.86 | ITGB2 (0.98) | ITGB2ICAM1ITGALKMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059880-A1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-10-12 | — | — | WO | disclosed |