Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 7/20 | 0.57 |
| ▸ | F12 | P00748 | 6/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691959 | 0.85 | F2 (1.00) | F2MEN1KMT2AMAOBF12 | |
| SCHEMBL7682475 | 0.84 | F2 (0.71) | F2MEN1KMT2AMAOBCA12 | |
| SCHEMBL7678753 | 0.84 | F2 (0.77) | F2MEN1KMT2AMAOBCA12 | |
| SCHEMBL18752550 | 0.83 | F2 (0.63) | F2MEN1KMT2AMAOBF12 | |
| SCHEMBL7682577 | 0.81 | MEN1 (0.63) | F2MEN1KMT2AMAOBF12 | |
| SCHEMBL13857249 | 0.80 | MAOB (0.69) | MEN1KMT2AMAOBF12CA12 | |
| SCHEMBL7682593 | 0.79 | MAOB (0.55) | F2MEN1KMT2AMAOBF12 | |
| SCHEMBL7678613 | 0.77 | MEN1 (0.57) | F2MEN1KMT2AMAOBF12 | |
| SCHEMBL18589240 | 0.77 | MAOB (0.70) | MAOBF12CA12CA1CA2 | |
| SCHEMBL18752204 | 0.76 | F2 (0.67) | F2MEN1KMT2AMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |