Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.90 |
| ▸ | SLC1A2 | P43004 | 7/20 | 0.68 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.68 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 6/20 | 0.48 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL1585734 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL14485411 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL14485408 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL5398677 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL11046268 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL6129075 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL1585733 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL9007523 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL6564498 | 1.00 | SLC7A5 (0.90) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 | |
| Leucine SCHEMBL25241602 | 0.95 | SLC7A5 (1.00) | SLC7A5SLC1A2SLC1A3SLC1A1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403602-B1 | Morphine-6-sulfate analogues and their use for the treatment of pain | THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2002-06-11 | — | — | US | disclosed |