Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571798 | 0.98 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7704175 | 0.98 | ADRB3 (0.51) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7094685 | 0.92 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7594274 | 0.92 | ADRB3 (0.65) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7234702 | 0.84 | ADRB3 (0.58) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7631822 | 0.84 | ADRB3 (0.57) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7096019 | 0.84 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7695357 | 0.84 | ADRB3 (0.54) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7621702 | 0.83 | ADRB3 (0.55) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7094525 | 0.82 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451814-B1 | SUBSTITUTED 4-((4-AMINO-5-HYDROXYPHENYL)-OXY-)PIPERIDINE ANALOGS; METABOLIC DISORDERS; ANTIDIABETIC AGENTS; ATHERO-SCLEROSIS, GASTROINTESTINAL DISORDERS, GLAUCOMA, NEUROGENETIC INFLAMMATION, OCULAR HYPERTENSION AND FREQUENT URINATION | WYETH | 2002-09-17 | — | — | US | disclosed |