Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.44 |
| ▸ | MEN1 | O00255 | 8/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676111 | 0.86 | KDM4E (0.44) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL7678998 | 0.85 | MEN1 (0.43) | KMT2AMEN1NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7670127 | 0.85 | KDM4E (0.46) | KMT2AMEN1CYP2C9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7672787 | 0.84 | KDM4E (0.47) | KMT2AMEN1CYP2C9NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7674032 | 0.84 | KDM4E (0.42) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL7678522 | 0.84 | FLT1 (0.41) | KMT2AMEN1NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL7672374 | 0.82 | KDM4E (0.47) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL7677465 | 0.81 | HTT (0.41) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL7671668 | 0.81 | FLT1 (0.42) | KMT2AMEN1NPC1RAB9AHTT | |
| SCHEMBL7672308 | 0.80 | FLT1 (0.42) | KMT2AMEN1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479514-B1 | FOR THE CONTROL OF HELICOBACTER BACTERIA IN INFECTED PATIENTS | ALTANA PHARMA AG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1086094-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999061438-A1 | QUINOLINE-AMINOMETHYL-PYRIDYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-12-02 | — | — | WO | disclosed |