Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.63 |
| ▸ | GRB2 | P62993 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680012 | 0.94 | PTPN1 (0.56) | PTPN1GRB2 | |
| SCHEMBL4651225 | 0.91 | PTPN1 (0.69) | PTPN1GRB2 | |
| SCHEMBL7679773 | 0.87 | PTPN1 (0.64) | PTPN1GRB2 | |
| SCHEMBL7675512 | 0.86 | PTPN1 (0.63) | PTPN1GRB2 | |
| SCHEMBL7673509 | 0.85 | PTPN1 (0.62) | PTPN1FOLH1 | |
| SCHEMBL7680767 | 0.85 | PTPN1 (0.62) | PTPN1GRB2 | |
| SCHEMBL7671358 | 0.84 | PTPN1 (0.62) | PTPN1GRB2 | |
| SCHEMBL4651199 | 0.81 | PTPN1 (0.57) | PTPN1 | |
| SCHEMBL4650909 | 0.81 | PTPN1 (0.55) | PTPN1 | |
| SCHEMBL4650251 | 0.79 | PTPN1 (0.62) | PTPN1GRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |