Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206838 | 0.81 | GRIK1 (0.40) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL729719 | 0.78 | — | — | |
| SCHEMBL27546558 | 0.77 | GRIK1 (0.53) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL731668 | 0.77 | SLC6A2 (0.36) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL6048344 | 0.77 | ABAT (0.33) | — | |
| SCHEMBL465932 | 0.77 | — | — | |
| SCHEMBL465931 | 0.77 | — | — | |
| SCHEMBL7675717 | 0.75 | GRIK1 (0.53) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL12191191 | 0.75 | GRIK1 (0.55) | GRIK1GRIA2GRIA4GRIK3GRIK5 | |
| SCHEMBL7171390 | 0.75 | GRIK1 (0.55) | GRIK1GRIA2GRIA4GRIK3GRIK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448340-B1 | CORE OR INTERMEDIATE LAYER FORMED OF BLEND OF HIGH ACID AND VERY LOW MUODULUS IONOMER (VLMI) RESINS; IMPROVED INITIAL VELOCITY AND RESILENCE | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2002-09-10 | — | — | US | claimed |