Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | GRB2 | P62993 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650251 | 0.81 | PTPN1 (0.62) | PTPN1L3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL7677844 | 0.80 | PTPN1 (0.54) | PTPN1L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL7677841 | 0.80 | PTPN1 (0.54) | PTPN1L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL7671358 | 0.79 | PTPN1 (0.62) | PTPN1L3MBTL1ALDH1A1LMNAPTGDR2 | |
| SCHEMBL4651320 | 0.79 | PTPN1 (0.60) | PTPN1 | |
| SCHEMBL4651102 | 0.78 | PTPN1 (0.61) | PTPN1ALDH1A1MAPTGRB2 | |
| SCHEMBL7675512 | 0.78 | PTPN1 (0.63) | PTPN1L3MBTL1ALDH1A1LMNATP53 | |
| SCHEMBL7679773 | 0.77 | PTPN1 (0.64) | PTPN1L3MBTL1ALDH1A1LMNAPTGDR2 | |
| SCHEMBL7680012 | 0.75 | PTPN1 (0.56) | PTPN1L3MBTL1ALDH1A1LMNAMAPT | |
| SCHEMBL4650268 | 0.75 | PTPN1 (0.58) | PTPN1HTTGRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539115-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | claimed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | claimed |
| US-6410585-B1 | THERAPY FOR NON-INSULIN DEPEND DIABETES | BIOVITRUM AB (SE) | 2002-06-25 | — | — | US | disclosed |
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |