Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 11/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 8/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83179 | 0.84 | NAMPT (0.63) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL82896 | 0.83 | NAMPT (0.65) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL82897 | 0.83 | NAMPT (0.65) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83013 | 0.82 | NAMPT (0.74) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83014 | 0.82 | NAMPT (0.74) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL3078740 | 0.81 | NAMPT (0.66) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83173 | 0.79 | NAMPT (0.70) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83174 | 0.79 | NAMPT (0.70) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83220 | 0.78 | NAMPT (0.65) | NAMPTCYP3A4CYP2C9ACHEBCHE | |
| SCHEMBL83221 | 0.78 | NAMPT (0.65) | NAMPTCYP3A4CYP2C9ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451816-B1 | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression | KLINGE PHARMA GMBH (DE) | 2002-09-17 | — | — | US | disclosed |