SCHEMBL7679307

SCHEMBL7679307

C1=Cc2ccccc2ON1.[Pb]

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
KMT2A Q03164 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
PARP1 P09874 1/20 0.33
ALOX5 P09917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29804885 0.98 MAPT (0.37) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL16341187 0.98 MAPT (0.37) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL8924 0.98 MAPT (0.37) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL3662203 0.98 MAPT (0.37) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL3201327 0.95 MAPT (0.36) MAPTGAAKDM4EMEN1ALDH1A1
Ammonia Solution, Strong SCHEMBL2017455 0.95 MAPT (0.36) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL584705 0.95 MAPT (0.36) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL7679297 0.95 MAPT (0.36) MAPTGAAKDM4EMEN1ALDH1A1
SCHEMBL21822066 0.95 MAPT (0.36) MAPTGAAKDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL8699853 0.95 PARP1 (0.38) MAPTGAAKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108431134-B Benzoxazine and phthalonitrile resin blends 3M创新有限公司 2021-03-09 CN disclosed
US-20020128354-A1 NOVEL HARDENER FOR EPOXY MOLDING COMPOUNDS COOKSON SINGAPORE PTE, LTD. (SG) 2002-09-12 US disclosed
US-6437026-B1 Hardener for epoxy molding compounds COOKSON SINGAPORE PTE LTD. (SG) 2002-08-20 US disclosed