Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA3 | P07451 | 2/20 | 0.51 |
| ▸ | CA6 | P23280 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679354 | 0.90 | CA12 (0.49) | CA12CA2CA3CA6CA7 | |
| SCHEMBL18752302 | 0.89 | CA12 (0.55) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7681986 | 0.86 | POLB (0.47) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7681951 | 0.86 | F2 (0.68) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14642387 | 0.84 | F2 (0.58) | CA12CA2CA3CA6CA7 | |
| SCHEMBL7682593 | 0.84 | MAOB (0.55) | CA12CA2CA3CA6CA7 | |
| SCHEMBL18752216 | 0.83 | CA12 (0.56) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14652703 | 0.82 | F2 (0.60) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14652632 | 0.82 | F2 (0.54) | CA12CA2CA3CA6CA7 | |
| SCHEMBL14652631 | 0.82 | F2 (0.54) | CA12CA2CA3CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |