Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791450 | 0.88 | GRIK1 (0.53) | GRIK1GRIK2TSHREP300FAAH | |
| SCHEMBL7677057 | 0.86 | EP300 (0.53) | GRIK1TSHREP300FAAH | |
| SCHEMBL1843574 | 0.85 | EP300 (0.56) | GRIK1TSHREP300FAAH | |
| SCHEMBL7674494 | 0.85 | EP300 (0.56) | GRIK1TSHREP300FAAH | |
| SCHEMBL5133417 | 0.83 | GRIK1 (0.47) | GRIK1GRIK2TSHRKDM4EALDH1A1 | |
| SCHEMBL5133416 | 0.83 | GRIK1 (0.47) | GRIK1GRIK2TSHRKDM4EALDH1A1 | |
| SCHEMBL6024966 | 0.83 | GRIK1 (0.47) | GRIK1GRIK2TSHRKDM4EALDH1A1 | |
| SCHEMBL28038003 | 0.82 | GRIK1 (0.35) | GRIK1GRIK2TSHRALDH1A1 | |
| SCHEMBL21352425 | 0.82 | GRIK1 (0.49) | GRIK1GRIK2TSHREP300FAAH | |
| SCHEMBL21352424 | 0.82 | GRIK1 (0.49) | GRIK1GRIK2TSHREP300FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448340-B1 | CORE OR INTERMEDIATE LAYER FORMED OF BLEND OF HIGH ACID AND VERY LOW MUODULUS IONOMER (VLMI) RESINS; IMPROVED INITIAL VELOCITY AND RESILENCE | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2002-09-10 | — | — | US | claimed |