Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 0.45 |
| ▸ | HTR2A | P28223 | 13/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151828 | 0.82 | HTR2A (0.62) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151890 | 0.79 | SLC6A4 (0.58) | SLC6A4HTR2AKCNH2HRH3SLC6A2 | |
| SCHEMBL6151509 | 0.74 | HTR2A (0.62) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151609 | 0.71 | HTR2A (0.71) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6152246 | 0.68 | HTR2A (0.64) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151710 | 0.67 | HTR2A (0.67) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151513 | 0.67 | HTR2A (0.70) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6151381 | 0.67 | HTR2A (0.62) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6152336 | 0.66 | HTR2A (0.81) | SLC6A4HTR2AKCNH2 | |
| SCHEMBL6152309 | 0.66 | HTR2A (0.61) | SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410736-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | PFIZER INC. | 2002-06-25 | — | — | US | claimed |