Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.78 |
| ▸ | F10 | P00742 | 5/20 | 0.78 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 2/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
| ▸ | PROC | P04070 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.47 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679895 | 1.00 | F2 (0.78) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7102654 | 0.99 | F2 (0.77) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7096375 | 0.91 | F2 (0.66) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL2989514 | 0.88 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL2471738 | 0.88 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL29456575 | 0.88 | F2 (1.00) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL4937696 | 0.87 | F2 (0.98) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL4445262 | 0.87 | F2 (0.98) | F2F10PRSS1PRSS2PRSS3 | |
| Tanogitran SCHEMBL7417719 | 0.87 | F2 (0.98) | F2F10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7413108 | 0.87 | F2 (0.97) | F2F10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6451832-B2 | E.G., 2-(AMINDINOPHENYLAMINOMETHYL)-1-METHYL-5-(1-(ETHOXY-CARBONYL-METHYLAMINO)-1 -(2,5-DIHYDROPYRROLOCARBONYL)-ETHYL)BENZIMIDAZOLE; ANTICOAGULANTS AND ANTITHROMBOLYTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-09-17 | — | — | US | claimed |