Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687014 | 0.91 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6584602 | 0.90 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL6584845 | 0.89 | EDNRA (0.68) | EDNRAEDNRB | |
| SCHEMBL7686818 | 0.86 | EDNRA (0.89) | EDNRAEDNRB | |
| SCHEMBL7684835 | 0.85 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7686836 | 0.82 | EDNRA (0.82) | EDNRAEDNRB | |
| SCHEMBL6582341 | 0.81 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL803855 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7682649 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL6582199 | 0.81 | EDNRA (0.89) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384070-B2 | RESTENOSIS, KIDNEY DISEASES, LUNG DISEASES | PFIZER INC. | 2002-05-07 | — | — | US | disclosed |
| US-6306852-B1 | INDOLE DERIVATIVES USEFUL IN THE TREATMENT OF A VARIETY OF DISEASES INCLUDING RESTENOSIS, RENAL FAILURE AND PULMONARY HYPERTENSION, AND TO PHARMACEUTICAL FORMULATIONS CONTAINING SUCH COMPOUNDS. | PFIZER INC. | 2001-10-23 | — | — | US | disclosed |
| US-6136843-A | CARDIOVASCULAR DISORDERS; KIDNEY DISORDERS | PFIZER INC (US) | 2000-10-24 | — | — | US | disclosed |
| US-6017945-A | USEFUL IN THE TREATMENT OF RESTENOSIS, RENAL FAILURE AND PULMONARY HYPERTENSION | PFIZER INC. (US) | 2000-01-25 | — | — | US | disclosed |