Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7680151 | 0.99 | KMT2A (0.43) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7680318 | 0.92 | KMT2A (0.41) | KMT2AMEN1MAPTLMNAHTR2A | |
| SCHEMBL7673749 | 0.88 | KMT2A (0.56) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7683625 | 0.88 | KMT2A (0.43) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7683795 | 0.87 | KMT2A (0.56) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7674244 | 0.86 | MAPKAPK2 (0.47) | KMT2AHTR2AHTR2CKDM4EMAPKAPK2 | |
| SCHEMBL7673692 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7683347 | 0.85 | KMT2A (0.56) | KMT2AMEN1MAPTLMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7682863 | 0.85 | KMT2A (0.43) | KMT2AMEN1MAPTLMNAHTR2A | |
| SCHEMBL7675338 | 0.85 | HTR2A (0.55) | KMT2AHTR2AHTR2CMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | claimed |
| US-6350757-B1 | Beta-carboline compounds | LES LABORATOIRES SERVIER (FR) | 2002-02-26 | — | — | US | disclosed |