Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.61 |
| ▸ | FNTB | P49356 | 18/20 | 0.61 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682385 | 1.00 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7687123 | 1.00 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7684988 | 1.00 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7683462 | 0.99 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7685251 | 0.84 | FNTA (0.61) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7665146 | 0.83 | FNTA (0.73) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7713343 | 0.82 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7713339 | 0.82 | FNTA (0.56) | FNTAFNTBPGGT1B | |
| SCHEMBL7680621 | 0.81 | FNTA (0.62) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7649954 | 0.81 | FNTA (0.62) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355643-B1 | ENZYME INHIBITORS, RAS GENES AND PROTEINS | MERCK & CO., INC. | 2002-03-12 | — | — | US | disclosed |